Voltarol (Diclofenac) — Patient Information (Australia)
Voltarol is a brand of diclofenac, a medicine from the non-steroidal anti-inflammatory drug (NSAID) family. It is used to relieve pain and inflammation in a range of conditions, including aches and strains, joint pain, and inflammatory conditions.
This guide explains how Voltarol works, when it may help, what to expect, how to use it safely, and important information about interactions—so you can make informed choices.
Quick facts
- Active ingredient: Diclofenac
- Drug class: NSAID (anti-inflammatory pain relief)
- Common forms available: Oral tablets and capsules, and topical gels/creams (depending on product range)
- Typical uses: Pain and inflammation due to musculoskeletal conditions (for example sprains, strains, arthritis-type pain) and other painful inflammatory problems as directed on the product information
- Key safety considerations: Stomach irritation/ulcers, increased cardiovascular risk in some people, kidney effects, and interactions with other medicines
How Voltarol works (mechanism of action)
Diclofenac reduces pain, swelling and inflammation by blocking enzymes called cyclooxygenases (COX-1 and COX-2). These enzymes help your body produce prostaglandins—substances that contribute to inflammation and pain.
By lowering prostaglandin production:
- Inflammation decreases, leading to reduced swelling and stiffness.
- Pain signals may lessen, improving comfort and movement.
- Fever-related pain pathways may be reduced (depending on the condition and formulation).
Important: Voltarol doesn’t cure the underlying condition. It helps manage symptoms (pain and inflammation) while you address the cause (for example rest, physiotherapy, or other medical management as appropriate).
Pharmacokinetics: what the body does with diclofenac
“Pharmacokinetics” describes how diclofenac is absorbed, distributed, metabolised and eliminated.
- Absorption: Oral diclofenac is absorbed through the gastrointestinal tract. The speed and extent can vary depending on formulation (e.g., immediate vs modified release).
- Distribution: Diclofenac binds substantially to blood proteins and distributes into tissues, including areas involved in inflammation.
- Metabolism: Diclofenac is primarily metabolised in the liver (mainly via CYP enzymes).
- Elimination: Metabolites are mainly cleared by the kidneys and partly via bile/faecal routes. Clearance can be slower in people with significant liver or kidney impairment.
These processes explain why certain conditions (such as liver or kidney disease) and drug interactions can change how safe or effective diclofenac is for an individual.
What Voltarol is typically used for
Voltarol is used for relief of pain and inflammation in a variety of conditions, particularly those affecting the muscles, joints, and soft tissues.
Common indications (depending on product type and strength):
- Musculoskeletal pain: sprains, strains, back pain, tendon/ligament pain
- Joint and arthritis-related pain: osteoarthritis, rheumatoid arthritis (symptom relief), and other inflammatory joint conditions
- Swelling and inflammation: flare-ups associated with inflammatory disorders (as per product guidance)
- Localised pain (topical forms): targeted relief for painful areas such as knees, hands, or injuries (depending on the gel/cream formulation)
Note: Availability and exact indications vary by formulation (oral vs topical), strength, and local product labelling. Always check the specific product carton or leaflet for approved uses.
When to take it: timing and duration
The best timing depends on the formulation and your symptom pattern.
General timing guidance
- For pain relief: Many people take diclofenac when symptoms are active (for example during the day) rather than continuously, but follow the product directions.
- Regular dosing: If you’re using an oral preparation designed for repeat dosing, you should space doses evenly according to the label.
- Topical diclofenac: Apply to clean, dry skin and follow the recommended frequency and amount. Wash hands after use unless the hands are the treated area.
How long to use
Use the lowest effective dose for the shortest time that controls your symptoms. If pain persists beyond a few days (or improves then worsens again), it’s sensible to seek advice from a pharmacist or healthcare professional.
Seek urgent advice if you develop severe allergic symptoms (such as facial swelling, wheeze, or hives) or signs of serious bleeding or stomach ulcers.
How to take Voltarol (dosing overview)
Because Voltarol comes in different strengths and formulations, dosing must match the specific product label and the condition being treated. Below is a general overview of typical dosing patterns.
| Formulation (examples) | Typical dosing approach | Notes |
|---|---|---|
| Oral tablets/capsules | Often taken once or more daily depending on whether the formulation is immediate-release or modified-release. | Do not exceed the maximum daily dose listed on your pack. Check whether you should take it with food. |
| Topical diclofenac gel/cream | Applied to the affected area typically a few times daily (frequency depends on the specific product). | Use only on intact skin; avoid eyes and mucous membranes. |
Always follow the directions on the packaging and the specific product information sheet. If you’re unsure, ask your pharmacist to confirm the correct dose for your exact Voltarol product.
Food interactions: what to eat and avoid
Food can affect how quickly and how well diclofenac is absorbed, and it can also influence stomach tolerance.
- Taking with food: Taking oral diclofenac with food may help reduce stomach irritation for some people.
- Avoid taking on an empty stomach if sensitive: If you have a history of stomach upset, reflux, gastritis, or ulcers, consider discussing with a pharmacist whether taking with meals is appropriate.
- No “specific” foods to ban: Unlike some antibiotics, diclofenac doesn’t require a long list of food restrictions. However, overall gut health matters—especially if you’re also taking other NSAIDs or blood thinners.
Topical forms: Food has less direct impact because systemic absorption is typically lower than with oral tablets, but you should still follow general safety advice.
Alcohol and medicine interactions
Alcohol can increase the risk of stomach bleeding and gastric irritation when used with NSAIDs. It can also worsen side effects like dizziness or indigestion.
- Advice: Limit alcohol while using diclofenac, especially if you have a history of ulcers or bleeding, or if you need higher doses or longer treatment.
- Be cautious with heavy drinking: Higher levels of alcohol may significantly raise bleeding risk.
Medicine interactions (important)
Diclofenac can interact with many commonly used medicines. These interactions may increase side effects, reduce effectiveness, or increase risk to the kidneys and stomach.
Examples of medicines that may interact with diclofenac
- Other NSAIDs (including ibuprofen, naproxen, and aspirin used for pain): increased risk of stomach bleeding and kidney effects.
- Anticoagulants (blood thinners) such as warfarin: increased bleeding risk.
- Antiplatelet agents (e.g., clopidogrel): increased bleeding risk.
- Corticosteroids (e.g., prednisone): higher risk of gastrointestinal irritation/ulcers.
- SSRIs/SNRIs (antidepressants): may increase bleeding risk in the gut when combined with NSAIDs.
- ACE inhibitors/ARBs and diuretics (blood pressure/heart/kidney medicines): combinations can affect kidney function in susceptible people.
- Lithium and methotrexate: diclofenac can increase levels or toxicity—requires careful monitoring.
- Digoxin: NSAIDs can raise digoxin levels in some circumstances.
- CYP-interacting medicines: diclofenac metabolism can be altered by certain drugs that affect liver enzymes.
Practical approach: Before starting Voltarol, tell your pharmacist or healthcare professional about all medicines you take, including:
- Prescription medicines
- Over-the-counter pain relievers and cold/flu products
- Herbal supplements (for example, certain products that affect bleeding risk)
- Any history of ulcers, bleeding, kidney problems, asthma triggered by NSAIDs, or heart disease
Indications and who should use with extra caution
Voltarol is designed to relieve symptoms of pain and inflammation. However, NSAIDs are not suitable for everyone.
Extra caution or avoid diclofenac if you:
- Have had an allergic reaction to diclofenac or other NSAIDs
- Have had asthma or breathing problems triggered by aspirin or NSAIDs
- Have a history of stomach ulcers, gastrointestinal bleeding, or severe reflux
- Have significant heart disease, stroke history, or uncontrolled high blood pressure (cardiovascular risk may be increased)
- Have kidney disease or dehydration (kidneys can be more vulnerable)
- Have significant liver disease
- Are pregnant (especially after 20 weeks; NSAIDs can affect the baby’s circulation later in pregnancy)
- Are breastfeeding (ask for advice on which products and dosing are safest)
If any of the above applies, it’s best to discuss options with a pharmacist to confirm the most appropriate analgesic strategy.
Safety profile: common side effects and serious warnings
Like all medicines, diclofenac can cause side effects. Many people tolerate it well when used correctly, but it’s important to recognise when to stop and seek help.
Common side effects (may occur)
- Indigestion, heartburn, stomach discomfort
- Nausea
- Headache
- Dizziness
- For topical products: skin irritation, redness, itching, rash at application site
Serious side effects: get urgent help
- Signs of allergy: swelling of face/lips, wheeze, severe rash, difficulty breathing
- Stomach bleeding: vomiting blood or material like “coffee grounds”, black/tarry stools, blood in stools
- Severe stomach pain or symptoms that suggest ulcer complications
- Chest pain, shortness of breath, weakness (possible cardiovascular events)
- Sudden reduction in urination or swelling of legs (possible kidney problems)
- Yellowing of skin/eyes or dark urine (possible liver issues)
Stop and seek advice immediately if you experience serious symptoms.
Practical use tips for safer, more comfortable relief
- Use the lowest effective dose: If you can control pain with less, choose the smaller amount.
- Short-term is usually best: If you need diclofenac for more than a few days, get advice.
- Don’t combine NSAIDs: Avoid taking diclofenac with other NSAIDs (unless your doctor specifically advised it).
- Consider gastric protection: If you’re at higher risk for stomach problems, a pharmacist can discuss safer alternatives or whether additional protection may be needed.
- Topical application: Apply to the targeted area only, do not cover with heat packs unless label permits, and wash hands after use.
- Avoid skin irritation: Don’t apply to broken skin or immediately after sun exposure; allow skin to cool.
- Stay hydrated: Dehydration increases kidney risk with NSAIDs.
- Know your history: If you previously had ulcers or cardiovascular events, discuss options before using diclofenac again.
Alternative options
If Voltarol isn’t suitable, alternatives may include other NSAIDs, paracetamol (acetaminophen), non-drug measures, and—depending on the condition—topical therapies or physiotherapy.
Common alternatives for pain and inflammation
- Paracetamol for pain relief (not an anti-inflammatory, but may be gentler on the stomach for many people)
- Other NSAIDs in appropriate cases (the safety profile differs; discuss with a pharmacist)
- Topical options such as other anti-inflammatory gels (use may reduce systemic exposure compared with tablets)
- Non-medication strategies: rest, ice/heat (as appropriate), gentle movement, strengthening exercises, and physiotherapy
If your pain is ongoing, spreading, or associated with swelling, fever, or injury, it’s important to get advice rather than repeatedly using pain relief.
Diclofenac in the Australian market: guidance and legal context
In Australia, access to medicines is regulated through the Therapeutic Goods Administration (TGA) and the Australian Register of Therapeutic Goods (ARTG). Medicines may be available:
- Over-the-counter (where permitted by product scheduling), or
- Through pharmacy/pharmacist advice, depending on strength and formulation, and/or
- By prescription for certain products or clinical situations
Always ensure you buy from reputable sources. Check the product name, active ingredient, strength, and expiry date. If you are unsure whether a product is appropriate for you, ask a pharmacist.
Recent safety and prescriber-focused caution has continued worldwide for NSAIDs, including diclofenac, highlighting cardiovascular and gastrointestinal risks, particularly with higher doses or longer duration. In Australia, consumer medicine information and professional guidance emphasise “use the lowest effective dose for the shortest possible time,” and careful screening for risk factors.
Note: Product ranges and availability can change. Your local pharmacy can help identify the best option among available diclofenac strengths or alternative treatments.
Delivery and availability (online pharmacy)
Voltarol may be available through online pharmacies depending on the form and strength. For home delivery:
- Packaging: Your order should arrive in manufacturer packaging with clear label information.
- Storage: Store as directed on the pack (typically in a cool, dry place, away from excessive heat).
- Expiry: Only use before the expiry date. Check the carton on arrival.
- Delivery timing: Delivery time varies by region and courier service. Most online pharmacies provide estimated delivery windows at checkout.
If you require assistance choosing between oral and topical forms, or selecting an appropriate strength, contact the pharmacy team before placing your order.
FAQ — Voltarol (Diclofenac)
1. What is Voltarol used for?
Voltarol (diclofenac) is used to relieve pain and inflammation in conditions such as muscle and joint pain, arthritis-related flare-ups, sprains, strains, and other inflammatory painful problems as stated on the product information.
2. Is Voltarol an anti-inflammatory?
Yes. Diclofenac is an NSAID that reduces inflammation by blocking COX enzymes and lowering prostaglandin production.
3. How quickly does it work?
Many people notice symptom relief within hours. Response can vary based on formulation (oral vs topical), dose, and the underlying condition.
4. Can I take Voltarol with food?
Yes, and for some people taking oral diclofenac with food helps reduce stomach irritation. If your pack advises “take with food,” follow that direction.
5. Can I drink alcohol while using Voltarol?
It’s best to limit alcohol. Combining alcohol with NSAIDs can increase the risk of stomach irritation and bleeding.
6. What happens if I miss a dose?
Take it when you remember unless it’s close to your next dose. Don’t take extra to “catch up.” For topical forms, apply at the next scheduled time according to the label.
7. Can I use Voltarol with other pain medicines?
Be careful. Avoid using other NSAIDs together. Paracetamol may be an alternative for pain relief, but check with a pharmacist if you have other medical conditions or take multiple medicines.
8. Are topical diclofenac products safer than tablets?
Topical diclofenac generally results in lower overall drug levels in the bloodstream compared with oral diclofenac, which may reduce certain systemic side effects. However, topical products can still cause reactions, and safety cautions still apply—especially in people with higher risk factors.
9. Who should avoid diclofenac?
People with a history of NSAID allergy, NSAID-triggered asthma, previous gastrointestinal bleeding/ulcers, significant kidney or liver impairment, certain heart risks, or those who are pregnant (particularly later pregnancy) should avoid or seek advice before use.
10. What side effects should make me stop and seek help?
Stop and seek urgent medical advice for signs of allergy, gastrointestinal bleeding (black stools or vomiting blood), severe stomach pain, breathing difficulties, chest pain, sudden weakness, fainting, or signs of kidney problems (marked decrease in urine, swelling).
11. Can diclofenac affect kidneys?
Yes. NSAIDs can reduce blood flow to the kidneys, which may be more risky if you’re dehydrated, have existing kidney disease, or take certain blood pressure/diuretic medicines. Stay hydrated and discuss risk if you’re in a high-risk group.
12. What if my pain doesn’t improve?
If pain persists, worsens, or returns repeatedly, you may need assessment for the underlying cause and a tailored treatment plan. Continue to use diclofenac only as short-term symptom management unless advised otherwise.
Summary
Voltarol (diclofenac) is a well-known NSAID for the relief of pain and inflammation associated with musculoskeletal conditions and certain inflammatory disorders. It works by reducing prostaglandin production. While many people use it effectively for short periods, safety matters—especially regarding stomach effects, cardiovascular risk, kidney effects, and interactions with other medicines and alcohol.
For best outcomes: use the lowest effective dose, follow the product label for timing and duration, avoid combining with other NSAIDs, and seek advice if symptoms persist or you have risk factors.

